Pistons are a concern but so too are the rods, crank, case and valve train (if we rev higher).
Wow, what an idea! I tried championing this a couple years ago and I'm still pulling the arrows from my back side. Good luck!
BTW, we actually got some dyno data on restrictor plates used with a higher flowing (Aussi spec) manifold. In the end anything "spec" was rejected out of the chute. Same with spec tires...
Bruce