I had a fairly detailed discussion via PM's with another ApexSpeed member on this subject. Since I thought it was generally useful, I reworded it a bit, and here it is.
Efficiency: Parallel vs Sequential Radiator Coolant Flow
The science is basically two-fold:
1. Whether there is parallel flow or sequential flow, if the amount of heat transferred to the air is the same, the difference in coolant temperature from engine exit to engine entry will be the same. If that is true, then that difference occurs whether there is sequential or parallel flow. So, given the above, the temperature difference between the beginning and end of the radiator flow path would be the same in either case. So, that does not result in or explain any difference.
2. The major difference between the two setups is the coolant-flow velocity through the radiators. The sequential setup will have twice the flow velocity through the radiators compared to the parallel setup. This increased velocity increases turbulence and decreases boundary layer thickness, both resulting in increased heat transfer efficiency between the coolant and the radiator tubes. It also reduces “dead” (places where coolant is mostly stagnant) volumes in the radiators. Therefore, since the radiator metal will run warmer, and more heat will be transferred to the air, the sequential setup will give greater cooling capacity for the same size radiators and coolant flow.
In addition, if the two flows in the parallel setup are not equal, even more advantage will be shown by the sequential setup.
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Q&A
a) Wouldn't the additional distance for the coolant to flow in the sequential setup reduce the mechanical efficiency of the flow?
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Maybe slightly, but that is mostly controlled by the WP efficiency. With sufficient coolant pipe and radiator sizes, that is not usually significant.
b) Will what holds true for high-speed track racing hold true for low-speed autocross?
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Yes – in this case, it is all relative, and the same principles hold.
c) Is it true that maximum coolant temperature entering each radiator will result in more heat transfer?
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The temperature entering the radiator(s) is only one value at one point. What is important is the total area of radiator at each coolant-temperature level. With either system the radiator area at any given coolant temperature level is the same, not counting differences in total heat transfer that would change the difference between enter and exit temperatures. At the risk of being redundant, that means whether parallel flow or sequential, area times temperature differential between radiator and air is the same, except for any differences resulting from efficiency.